Prediction of
the impact of non-synonymous Single Nucleotide Polymorphisms (nsSNPs)
on protein stability starting from protein 3D structure. Please, use the form below to submit
a valid protein PDB file (only PDB format is accepted, no mmCIF) along with a mutation file listing the variations
for which you want to predict the ΔΔG.
See the Help page for more details.
INPS-3D is described in the following article:
Castrense Savojardo, Piero Fariselli, Pier Luigi Martelli, Rita Casadio (2016)
INPS-MD: a web server to
predict stability of protein
variants from sequence and structure,
Bioinformatics, 32(16),2542–2544.